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KMID : 0360319930250020202
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Journal of Korean Cancer Research Association
1993 Volume.25 No. 2 p.202 ~ p.212
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A Case-Control Study on Protective Effect of Breast Feeding Against Breast Cancer among Postmenopausal Wonem in Korea
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Abstract
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A case-control study was conducted to investigate protective effect of breast feeding against breast cancer in Korea. Included in the analysis were 162 women, identified as having a histologically-confirmed diagnosis of breast cancer in a
hospital.
The
150 hospital-controls were women free of any malignant neoplasms nor other systematic diseases. Randomly selected neighborhoods and frieds of the patients(n=149) were also included as community controls in the analysis. Information on risk
factors
of
breast cancer was collected by selfadministered questionnaire. Statistical adjustment for potential confounders as well as a likelihood ratio test for trend was done by multivariate linear logistic regression model. Among postmenopausal-parous
women,
the risk of breast cancer was decreasing with increasing number of breastfed children(X2trend-4.2(1) for hospital controls; X2trend-1.2(1) for community controls). The trend of decreasing risk with increasing total months of breast feeding was
also
observed. Particularly noteworthy was a significant decreasing trend of breast cancer risk with months of breast feeding of the first child, regardless of parity and age at first full term pregnancy, This study confirmed an independent protective
effect
of breast feeding against breast cancer among postmenopausal women in Korea. These findings suggest that evasion of breast feeding may play a role in recent increase of breast cancer in Korea.
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KEYWORD
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